Vaginal microbicides
نویسندگان
چکیده
منابع مشابه
Vaginal microbicides.
The focus of this review will be to highlight articles from 2000 and up to August 2001 that demonstrate the challenges in the evaluation of candidate microbicides, and the ways in which investigators have approached these challenges.
متن کاملWomen's interest in vaginal microbicides.
CONTEXT Each year, an estimated 15 million new cases of sexually transmitted diseases (STDs), including HIV, occur in the United States. Women are not only at a disadvantage because of their biological and social susceptibility, but also because of the methods that are available for prevention. METHODS A nationally representative sample of 1,000 women aged 18-44 in the continental United Stat...
متن کاملVaginal rings for delivery of HIV microbicides
Following the successful development of long-acting steroid-releasing vaginal ring devices for the treatment of menopausal symptoms and contraception, there is now considerable interest in applying similar devices to the controlled release of microbicides against HIV. In this review article, the vaginal ring concept is first considered within the wider context of the early advances in controlle...
متن کاملPotential Use of Antimicrobial Peptides as Vaginal Spermicides/Microbicides.
The concurrent increases in global population and sexually transmitted infection (STI) demand a search for agents with dual spermicidal and microbicidal properties for topical vaginal application. Previous attempts to develop the surfactant spermicide, nonoxynol-9 (N-9), into a vaginal microbicide were unsuccessful largely due to its inefficiency to kill microbes. Furthermore, N-9 causes damage...
متن کاملMen’s Attitudes Toward Vaginal Microbicides And Microbicide Trials in Zimbabwe
preceding the DHS survey, as did 0.2% of married women. In addition, 7% of men reported that they had paid for sex during the same time period. It seems unlikely that in the near future levels of male condom use, abstinence or adherence to mutually faithful relationships will increase so significantly in Zimbabwe that the HIV epidemic will be slowed or stopped.3 Given the previous success of fe...
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ژورنال
عنوان ژورنال: International Journal of Infectious Diseases
سال: 2002
ISSN: 1201-9712
DOI: 10.1016/s1201-9712(02)90212-2